# Safety and Efficacy of the Use of Tissue Plasminogen Activator (tPA) in Intra-Abdominal Collections in Children - A Prospective Study

> **NCT01576679** · PHASE3 · TERMINATED · sponsor: **The Hospital for Sick Children** · enrollment: 28 (actual)

## Conditions studied

- Intra-abdominal Abscess

## Interventions

- **DRUG:** Cathflo (Alteplase)
- **DRUG:** Saline

## Key facts

- **NCT ID:** NCT01576679
- **Lead sponsor:** The Hospital for Sick Children
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2012-03
- **Primary completion:** 2016-05
- **Final completion:** 2017-06
- **Target enrollment:** 28 (ACTUAL)
- **Why stopped:** very slow accrual.
- **Last updated:** 2019-06-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01576679

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01576679, "Safety and Efficacy of the Use of Tissue Plasminogen Activator (tPA) in Intra-Abdominal Collections in Children - A Prospective Study". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT01576679. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*