# Early Stage Amyotrophic Lateral Sclerosis Phrenic Stimulation

> **NCT01583088** · PHASE3 · TERMINATED · sponsor: **Assistance Publique - Hôpitaux de Paris** · enrollment: 74 (actual)

## Conditions studied

- Amyotrophic Lateral Sclerosis
- Respiratory Insufficiency

## Interventions

- **DEVICE:** phenique nerve stimulation NeurX™ (Synapse Biomedical)
- **DEVICE:** sham phrenic nerve stimulation

## Key facts

- **NCT ID:** NCT01583088
- **Lead sponsor:** Assistance Publique - Hôpitaux de Paris
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2012-09
- **Primary completion:** 2015-11
- **Final completion:** 2015-11
- **Target enrollment:** 74 (ACTUAL)
- **Why stopped:** in the absence of benefits and because of a statistically significant excess mortality in the group of patients receiving active stimulation.
- **Last updated:** 2015-12-22

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01583088

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01583088, "Early Stage Amyotrophic Lateral Sclerosis Phrenic Stimulation". Retrieved via AI Analytics 2026-06-15 from https://api.ai-analytics.org/clinical/NCT01583088. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*