# Cardiovascular Inflammation Reduction Trial

> **NCT01594333** · PHASE3 · COMPLETED · sponsor: **Brigham and Women's Hospital** · enrollment: 4786 (actual)

## Conditions studied

- Cardiovascular Disease

## Interventions

- **DRUG:** Methotrexate
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01594333
- **Lead sponsor:** Brigham and Women's Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-04
- **Primary completion:** 2019-04-15
- **Final completion:** 2019-10-30
- **Target enrollment:** 4786 (ACTUAL)
- **Last updated:** 2020-07-24

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01594333

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01594333, "Cardiovascular Inflammation Reduction Trial". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01594333. Licensed CC0.

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