# Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors

> **NCT01596647** · PHASE1 · COMPLETED · sponsor: **Novartis Pharmaceuticals** · enrollment: 39 (actual)

## Conditions studied

- Advanced Solid Tumors, Excluding Breast Cancer

## Interventions

- **DRUG:** caffeine
- **DRUG:** diclofenac
- **DRUG:** omeprazole
- **DRUG:** midazolam
- **DRUG:** TKI258

## Key facts

- **NCT ID:** NCT01596647
- **Lead sponsor:** Novartis Pharmaceuticals
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2012-05
- **Primary completion:** 2014-07
- **Final completion:** 2014-07
- **Target enrollment:** 39 (ACTUAL)
- **Last updated:** 2020-12-21


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01596647

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01596647, "Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors". Retrieved via AI Analytics 2026-05-30 from https://api.ai-analytics.org/clinical/NCT01596647. Licensed CC0.

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