# Effects of Methylnaltrexone in Comparison to Naloxone on Loperamide-induced Delay of the Oro-cecal, Whole-gut and Colon Transit Time.

> **NCT01596764** · PHASE1 · COMPLETED · sponsor: **University Medicine Greifswald** · enrollment: 16 (actual)

## Conditions studied

- Intestinal Obstruction

## Interventions

- **DRUG:** Loperamide placebo
- **DRUG:** Loperamide
- **DEVICE:** Colon Transit
- **DRUG:** Sulfasalazine
- **DRUG:** Placebo of MNTX and NLX
- **DRUG:** Naloxone
- **DRUG:** Methylnaltrexone

## Key facts

- **NCT ID:** NCT01596764
- **Lead sponsor:** University Medicine Greifswald
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-05
- **Primary completion:** 2011-07
- **Final completion:** 2012-01
- **Target enrollment:** 16 (ACTUAL)
- **Last updated:** 2012-05-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01596764

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01596764, "Effects of Methylnaltrexone in Comparison to Naloxone on Loperamide-induced Delay of the Oro-cecal, Whole-gut and Colon Transit Time.". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT01596764. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*