# A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

> **NCT01625351** · PHASE1 · COMPLETED · sponsor: **St. Jude Children's Research Hospital** · enrollment: 23 (actual)

## Conditions studied

- Ewing Sarcoma
- Gastrointestinal Tumor
- Germ Cell Tumor
- Hepatic Tumor
- Lymphoma
- Wilms Tumor
- Rhabdoid Tumor
- Clear Cell Carcinoma
- Renal Cell Carcinoma
- Melanoma
- Neuroblastoma
- Rhabdomyosarcoma
- Non-rhabdomyosarcoma

## Interventions

- **DRUG:** alemtuzumab
- **DRUG:** fludarabine
- **DRUG:** sirolimus
- **DRUG:** Busulfan
- **DRUG:** melphalan
- **BIOLOGICAL:** stem cells
- **DEVICE:** CliniMACS

## Key facts

- **NCT ID:** NCT01625351
- **Lead sponsor:** St. Jude Children's Research Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2012-08-20
- **Primary completion:** 2020-02-10
- **Final completion:** 2020-02-10
- **Target enrollment:** 23 (ACTUAL)
- **Last updated:** 2026-02-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01625351

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01625351, "A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT01625351. Licensed CC0.

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