# Effect of Neurokinin-1 Receptor (NK1R) Antagonism on Pruritus in Patients With Sezary Syndrome

> **NCT01625455** · PHASE4 · TERMINATED · sponsor: **Vanderbilt University Medical Center** · enrollment: 7 (actual)

## Conditions studied

- Sezary Syndrome
- Pruritus

## Interventions

- **DRUG:** Aprepitant
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01625455
- **Lead sponsor:** Vanderbilt University Medical Center
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2012-02
- **Primary completion:** 2015-07
- **Final completion:** 2016-07
- **Target enrollment:** 7 (ACTUAL)
- **Why stopped:** Difficulty recruiting.
- **Last updated:** 2017-05-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01625455

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01625455, "Effect of Neurokinin-1 Receptor (NK1R) Antagonism on Pruritus in Patients With Sezary Syndrome". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT01625455. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*