# Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction

> **NCT01638533** · PHASE1 · COMPLETED · sponsor: **National Cancer Institute (NCI)** · enrollment: 37 (actual)

## Conditions studied

- Glioma
- Hematopoietic and Lymphoid Cell Neoplasm
- Lymphoma
- Metastatic Malignant Solid Neoplasm
- Neuroendocrine Neoplasm
- Recurrent Adult Soft Tissue Sarcoma
- Recurrent Bladder Carcinoma
- Recurrent Breast Carcinoma
- Recurrent Chronic Lymphocytic Leukemia
- Recurrent Colorectal Carcinoma
- Recurrent Head and Neck Carcinoma
- Recurrent Lung Carcinoma
- Recurrent Malignant Solid Neoplasm
- Recurrent Melanoma
- Recurrent Pancreatic Carcinoma
- Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
- Recurrent Prostate Carcinoma
- Recurrent Renal Cell Carcinoma
- Recurrent Thyroid Gland Carcinoma
- Refractory Chronic Lymphocytic Leukemia
- Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma
- Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma
- Stage III Breast Cancer AJCC v7
- Stage III Colorectal Cancer AJCC v7
- Stage III Cutaneous Melanoma AJCC v7
- Stage III Lung Cancer AJCC v7
- Stage III Pancreatic Cancer AJCC v6 and v7
- Stage III Prostate Cancer AJCC v7
- Stage III Renal Cell Cancer AJCC v7
- Stage III Soft Tissue Sarcoma AJCC v7
- Stage IIIA Breast Cancer AJCC v7
- Stage IIIA Colorectal Cancer AJCC v7
- Stage IIIA Cutaneous Melanoma AJCC v7
- Stage IIIB Breast Cancer AJCC v7
- Stage IIIB Colorectal Cancer AJCC v7
- Stage IIIB Cutaneous Melanoma AJCC v7
- Stage IIIC Breast Cancer AJCC v7
- Stage IIIC Colorectal Cancer AJCC v7
- Stage IIIC Cutaneous Melanoma AJCC v7
- Stage IV Breast Cancer AJCC v6 and v7
- Stage IV Colorectal Cancer AJCC v7
- Stage IV Cutaneous Melanoma AJCC v6 and v7
- Stage IV Lung Cancer AJCC v7
- Stage IV Pancreatic Cancer AJCC v6 and v7
- Stage IV Prostate Cancer AJCC v7
- Stage IV Renal Cell Cancer AJCC v7
- Stage IV Soft Tissue Sarcoma AJCC v7
- Stage IVA Colorectal Cancer AJCC v7
- Stage IVB Colorectal Cancer AJCC v7
- Unresectable Solid Neoplasm

## Interventions

- **OTHER:** Pharmacological Study
- **DRUG:** Romidepsin

## Key facts

- **NCT ID:** NCT01638533
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2012-08-03
- **Primary completion:** 2018-11-29
- **Final completion:** 2020-09-01
- **Target enrollment:** 37 (ACTUAL)
- **Last updated:** 2025-02-07

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01638533

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01638533, "Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01638533. Licensed CC0.

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