Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transplant

NCT01640301 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

TERMINATED

Status

47

Enrollment

OTHER

Sponsor class

Stopped Terminated due to slow accrual.

Conditions

Recurrent Adult Acute Myeloid Leukemia
Recurrent Childhood Acute Myeloid Leukemia
Secondary Acute Myeloid Leukemia
Therapy-Related Acute Myeloid Leukemia
Donor
Hematopoietic Cell Transplant Recipient
HLA-A*0201 Positive Cells Present
Recurrent Acute Myeloid Leukemia

Interventions

BIOLOGICAL: Aldesleukin
DRUG: Cyclophosphamide
DRUG: Fludarabine Phosphate
OTHER: Laboratory Biomarker Analysis
BIOLOGICAL: WT1-Sensitized Allogeneic T-Lymphocytes

Sponsor

Fred Hutchinson Cancer Center

Collaborators

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