# Large-scale Trial Testing the Intensity of CYTOreductive Therapy in Polycythemia Vera (PV)

> **NCT01645124** · PHASE3 · TERMINATED · sponsor: **Consorzio Mario Negri Sud** · enrollment: 365 (actual)

## Conditions studied

- Polycythemia Vera

## Interventions

- **DRUG:** Hydroxyurea
- **PROCEDURE:** Phlebotomy

## Key facts

- **NCT ID:** NCT01645124
- **Lead sponsor:** Consorzio Mario Negri Sud
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2008-05
- **Primary completion:** 2012-06
- **Final completion:** 2012-07
- **Target enrollment:** 365 (ACTUAL)
- **Why stopped:** Low accrual rate not allowing planned sample size leads to a futility condition
- **Last updated:** 2012-07-20

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01645124

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01645124, "Large-scale Trial Testing the Intensity of CYTOreductive Therapy in Polycythemia Vera (PV)". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT01645124. Licensed CC0.

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