# Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy

> **NCT01682031** · PHASE2 · TERMINATED · sponsor: **Roswell Park Cancer Institute** · enrollment: 18 (actual)

## Conditions studied

- Chemotherapeutic Agent Toxicity
- Mucositis
- Radiation Toxicity
- Stage III Squamous Cell Carcinoma of the Hypopharynx
- Stage III Squamous Cell Carcinoma of the Larynx
- Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity
- Stage III Squamous Cell Carcinoma of the Nasopharynx
- Stage III Squamous Cell Carcinoma of the Oropharynx
- Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
- Stage IV Squamous Cell Carcinoma of the Hypopharynx
- Stage IV Squamous Cell Carcinoma of the Larynx
- Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity
- Stage IV Squamous Cell Carcinoma of the Nasopharynx
- Stage IV Squamous Cell Carcinoma of the Oropharynx
- Stage IV Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity
- Xerostomia

## Interventions

- **DIETARY_SUPPLEMENT:** selenomethionine
- **OTHER:** placebo
- **DRUG:** cisplatin
- **RADIATION:** radiation therapy
- **PROCEDURE:** quality-of-life assessment

## Key facts

- **NCT ID:** NCT01682031
- **Lead sponsor:** Roswell Park Cancer Institute
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2009-06
- **Primary completion:** 2012-04
- **Final completion:** 2012-06
- **Target enrollment:** 18 (ACTUAL)
- **Why stopped:** Due to a lack of funding
- **Last updated:** 2014-08-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01682031

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01682031, "Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01682031. Licensed CC0.

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