# Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma

> **NCT01700946** · PHASE2 · COMPLETED · sponsor: **St. Jude Children's Research Hospital** · enrollment: 80 (actual)

## Conditions studied

- Recurrent B-Cell Childhood Acute Lymphoblastic Leukemia
- Recurrent Childhood B-Lymphoblastic Lymphoma

## Interventions

- **DRUG:** dexamethasone
- **DRUG:** vincristine sulfate
- **BIOLOGICAL:** rituximab
- **DRUG:** clofarabine
- **DRUG:** cyclophosphamide
- **DRUG:** etoposide
- **BIOLOGICAL:** aldesleukin
- **DRUG:** pegaspargase
- **DRUG:** methotrexate
- **DRUG:** mercaptopurine
- **DRUG:** cytarabine
- **DRUG:** mitoxantrone
- **DRUG:** teniposide
- **DRUG:** vinblastine
- **BIOLOGICAL:** natural killer cell infusion
- **OTHER:** laboratory biomarker analysis
- **DRUG:** therapeutic hydrocortisone
- **PROCEDURE:** allogeneic hematopoietic stem cell transplantation
- **DEVICE:** CliniMACS

## Key facts

- **NCT ID:** NCT01700946
- **Lead sponsor:** St. Jude Children's Research Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-04-15
- **Primary completion:** 2021-07-24
- **Final completion:** 2021-07-24
- **Target enrollment:** 80 (ACTUAL)
- **Last updated:** 2022-09-28

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01700946

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01700946, "Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT01700946. Licensed CC0.

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