Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IV Head and Neck Cancer

NCT01711541 · clinicaltrials.gov ↗

PHASE1,PHASE2

Phase

COMPLETED

Status

24

Enrollment

NIH

Sponsor class

Conditions

Head and Neck Squamous Cell Carcinoma
Stage IVA Oropharyngeal Carcinoma AJCC v7
Stage IVB Oropharyngeal Carcinoma AJCC v7

Interventions

DRUG: Carboplatin
DRUG: Cisplatin
DRUG: Fluorouracil
DRUG: Hydroxyurea
OTHER: Laboratory Biomarker Analysis
DRUG: Paclitaxel
OTHER: Placebo Administration
RADIATION: Radiation Therapy
DRUG: Veliparib

Sponsor

National Cancer Institute (NCI)