# NEOadjuvant Trial in Adenocarcinoma of the oEsophagus and oesophagoGastric Junction International Study (Neo-AEGIS)

> **NCT01726452** · PHASE3 · COMPLETED · sponsor: **Cancer Trials Ireland** · enrollment: 377 (actual)

## Conditions studied

- Adenocarcinoma of the Oesophagus
- Adenocarcinoma of the Oesophago-gastric Junction
- Oesophageal Tumours
- Junctional Tumours
- Oesophageal Cancer

## Interventions

- **DRUG:** Epirubicin
- **DRUG:** Cisplatin / Oxaliplatin
- **DRUG:** 5 Flourouracil/ Capecitabine
- **RADIATION:** (41.4 Gy/23 fractions)
- **DRUG:** Paclitaxel
- **DRUG:** Carboplatin
- **DRUG:** Docetaxel
- **DRUG:** Oxaliplatin
- **DRUG:** Leucovorin
- **DRUG:** 5-Fluorouracil

## Key facts

- **NCT ID:** NCT01726452
- **Lead sponsor:** Cancer Trials Ireland
- **Sponsor class:** NETWORK
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-01-24
- **Primary completion:** 2022-08-04
- **Final completion:** 2022-08-04
- **Target enrollment:** 377 (ACTUAL)
- **Last updated:** 2022-09-30

## Collaborators

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- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01726452

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01726452, "NEOadjuvant Trial in Adenocarcinoma of the oEsophagus and oesophagoGastric Junction International Study (Neo-AEGIS)". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01726452. Licensed CC0.

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