LCCC 1128: Open Label Phase II Trial of the BRAF Inhibitor (Dabrafenib) and the MEK Inhibitor (Trametinib) in Unresectable Stage III and Stage IV BRAF Mutant Melanoma; Correlation of Resistance With the Kinome and Functional Mutations
Conditions
- Stage III Melanoma
- Stage IV Melanoma
- Unresectable Melanoma
- BRAF Mutant Melanoma
Interventions
- DRUG: BRAF inhibitor dabrafenib and MEK inhibitor trametinib
Sponsor
UNC Lineberger Comprehensive Cancer Center
Collaborators