# A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches Using the ChAd63 and MVA Vectors Encoding the Antigens ME-TRAP, CS and AMA1

> **NCT01739036** · PHASE1,PHASE2 · COMPLETED · sponsor: **University of Oxford** · enrollment: 48 (actual)

## Conditions studied

- Plasmodium Falciparum Malaria

## Interventions

- **BIOLOGICAL:** ChAd63 CS/ME-TRAP
- **BIOLOGICAL:** MVA CS/ME-TRAP
- **BIOLOGICAL:** ChAd63 CS/ME-TRAP/AMA1
- **BIOLOGICAL:** MVA CS/ME-TRAP/AMA1
- **OTHER:** Controlled Human Malaria Infection Administered by Mosquito Bite

## Key facts

- **NCT ID:** NCT01739036
- **Lead sponsor:** University of Oxford
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-01
- **Primary completion:** 2013-10
- **Final completion:** 2013-10
- **Target enrollment:** 48 (ACTUAL)
- **Last updated:** 2013-11-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01739036

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01739036, "A Phase I/IIa Sporozoite Challenge Study to Assess the Efficacy of Candidate Combination Malaria Vaccine Approaches Using the ChAd63 and MVA Vectors Encoding the Antigens ME-TRAP, CS and AMA1". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01739036. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*