# Study to Evaluate Safety, Tolerability and Pharmacokinetics of rhNGF Eye Drops in Healthy Volunteers

> **NCT01744704** · PHASE1 · COMPLETED · sponsor: **Dompé Farmaceutici S.p.A** · enrollment: 74 (actual)

## Conditions studied

- Healthy

## Interventions

- **DRUG:** rhNGF 0.5 µg/mL Sentinel
- **DRUG:** rhNGF 5 µg/mL Sentinel
- **DRUG:** rhNGF 20 µg/mL Sentinel
- **DRUG:** rhNGF 20 µg/mL Part A
- **DRUG:** rhNGF 60 µg/mL Part A
- **DRUG:** rhNGF 180 µg/mL Part A
- **DRUG:** rhNGF 20 µg/mL Part B
- **DRUG:** rhNGF 60 µg/mL Part B
- **DRUG:** rhNGF 180 µg/mL Part B
- **DRUG:** Placebo Part A
- **DRUG:** Placebo Part B

## Key facts

- **NCT ID:** NCT01744704
- **Lead sponsor:** Dompé Farmaceutici S.p.A
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2012-07
- **Primary completion:** 2013-02
- **Final completion:** 2013-03
- **Target enrollment:** 74 (ACTUAL)
- **Last updated:** 2024-04-19

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01744704

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01744704, "Study to Evaluate Safety, Tolerability and Pharmacokinetics of rhNGF Eye Drops in Healthy Volunteers". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT01744704. Licensed CC0.

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