# Comparison of 20% Mannitol and 3% Hypertonic Saline for Cerebral Relaxation During Elective Supratentorial Craniotomies

> **NCT01745081** · PHASE4 · UNKNOWN · sponsor: **Université de Sherbrooke** · enrollment: 80 (estimated)

## Conditions studied

- Osmotherapy
- Intracranial Pressure

## Interventions

- **DRUG:** 20% mannitol bolus administration
- **DRUG:** Hypertonic saline 3% bolus administration

## Key facts

- **NCT ID:** NCT01745081
- **Lead sponsor:** Université de Sherbrooke
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2012-09
- **Primary completion:** 2014-09
- **Final completion:** 2014-09
- **Target enrollment:** 80 (ESTIMATED)
- **Last updated:** 2012-12-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01745081

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01745081, "Comparison of 20% Mannitol and 3% Hypertonic Saline for Cerebral Relaxation During Elective Supratentorial Craniotomies". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT01745081. Licensed CC0.

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