# Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic Encephalopathy

> **NCT01765218** · PHASE1,PHASE2 · TERMINATED · sponsor: **Kristin R Hoffman** · enrollment: 34 (actual)

## Conditions studied

- Hypoxic Ischemic Encephalopathy

## Interventions

- **DRUG:** Topiramate
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01765218
- **Lead sponsor:** Kristin R Hoffman
- **Sponsor class:** OTHER
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2013-02
- **Primary completion:** 2022-01-27
- **Final completion:** 2022-01-27
- **Target enrollment:** 34 (ACTUAL)
- **Why stopped:** The study was stopped early due to changes in the UC Davis guidelines on who qualified for therapeutic hypothermia and significant difficulty in recruitment of patients following the COVID19 pandemic.
- **Last updated:** 2024-06-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01765218

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01765218, "Topiramate in Neonates Receiving Whole Body Cooling for Hypoxic Ischemic Encephalopathy". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT01765218. Licensed CC0.

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