# Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT): A Feasibility Clinical Trial

> **NCT01782755** · PHASE2 · COMPLETED · sponsor: **McMaster University** · enrollment: 150 (actual)

## Conditions studied

- Ventilator Associated Pneumonia (VAP)
- Other Infections
- Antibiotic-Associated Diarrhea
- C-Difficile
- Duration of Mechanical Ventilation
- Length of ICU Stay
- Length of Hospital Stay
- ICU and Hospital Mortality

## Interventions

- **DRUG:** L. rhamnosus GG - Probiotic
- **OTHER:** Placebo - Microcrystalline Cellulose

## Key facts

- **NCT ID:** NCT01782755
- **Lead sponsor:** McMaster University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-10
- **Primary completion:** 2014-08
- **Final completion:** 2015-01
- **Target enrollment:** 150 (ACTUAL)
- **Last updated:** 2019-08-28

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01782755

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01782755, "Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT): A Feasibility Clinical Trial". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01782755. Licensed CC0.

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