# Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma

> **NCT01783535** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **St. Jude Children's Research Hospital** · enrollment: 174 (estimated)

## Conditions studied

- Retinoblastoma

## Interventions

- **DRUG:** vincristine
- **DRUG:** topotecan
- **DRUG:** filgrastim
- **DRUG:** PEG-filgrastim
- **DRUG:** carboplatin
- **OTHER:** focal therapy
- **DRUG:** etoposide
- **DRUG:** cyclophosphamide
- **DRUG:** MESNA
- **DRUG:** doxorubicin
- **PROCEDURE:** enucleation
- **RADIATION:** external beam radiation or proton beam radiation

## Key facts

- **NCT ID:** NCT01783535
- **Lead sponsor:** St. Jude Children's Research Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2013-06-19
- **Primary completion:** 2023-03-17
- **Final completion:** 2028-01
- **Target enrollment:** 174 (ESTIMATED)
- **Last updated:** 2024-04-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01783535

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01783535, "Protocol for the Study and Treatment of Participants With Intraocular Retinoblastoma". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01783535. Licensed CC0.

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