# Randomized Controlled Trial to Evaluate the Optimal Timing of Surgical Antimicrobial Prophylaxis

> **NCT01790529** · PHASE4 · COMPLETED · sponsor: **University Hospital, Basel, Switzerland** · enrollment: 5000 (actual)

## Conditions studied

- Surgical Site Infection

## Interventions

- **PROCEDURE:** Early administration of SAP (Cefuroxime (plus metronidazole in colorectal surgery)) in anesthetic room (75 to 30 minutes prior to skin incision)
- **PROCEDURE:** Late administration of SAP (Cefuroxime (plus metronidazole in colorectal surgery)) in the operating theatre (within 30 minutes prior to skin incision)

## Key facts

- **NCT ID:** NCT01790529
- **Lead sponsor:** University Hospital, Basel, Switzerland
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-02
- **Primary completion:** 2015-07
- **Final completion:** 2016-09
- **Target enrollment:** 5000 (ACTUAL)
- **Last updated:** 2016-09-29

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01790529

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01790529, "Randomized Controlled Trial to Evaluate the Optimal Timing of Surgical Antimicrobial Prophylaxis". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT01790529. Licensed CC0.

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