# Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma

> **NCT01795430** · NA · WITHDRAWN · sponsor: **City of Hope Medical Center**

## Conditions studied

- Adult Supratentorial Primitive Neuroectodermal Tumor (PNET)
- Ewing Sarcoma of Bone
- Extraosseous Ewing Sarcoma
- Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
- Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor
- Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
- Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor

## Interventions

- **DRUG:** etoposide
- **DRUG:** ifosfamide
- **RADIATION:** intensity-modulated radiation therapy
- **DRUG:** topotecan hydrochloride
- **DRUG:** busulfan
- **DRUG:** melphalan
- **PROCEDURE:** autologous hematopoietic stem cell transplantation
- **PROCEDURE:** peripheral blood stem cell transplantation
- **PROCEDURE:** autologous bone marrow transplantation

## Key facts

- **NCT ID:** NCT01795430
- **Lead sponsor:** City of Hope Medical Center
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2013-07
- **Primary completion:** 2018-03
- **Final completion:** —
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** No participants enrolled.
- **Last updated:** 2015-01-09

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01795430

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01795430, "Whole-Body Radiation Therapy, Systemic Chemotherapy, and High-Dose Chemotherapy Followed By Stem Cell Rescue in Treating Patients With Poor-Risk Ewing Sarcoma". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01795430. Licensed CC0.

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