# RCT Comparing the Analgesic Efficacy of 4 Therapeutic Strategies Based on 4 Different Major Opioids (Fentanyl, Oxycodone, Buprenorphine vs Morphine) in Cancer Patients With Moderate/Severe Pain, at the Moment of Starting 3rd Step of WHO Analgesic Ladder.

> **NCT01809106** · PHASE4 · COMPLETED · sponsor: **Mario Negri Institute for Pharmacological Research** · enrollment: 518 (actual)

## Conditions studied

- Cancer
- Cancer Pain

## Interventions

- **DRUG:** Morphine
- **DRUG:** Fentanyl
- **DRUG:** Buprenorphine
- **DRUG:** Oxycodone

## Key facts

- **NCT ID:** NCT01809106
- **Lead sponsor:** Mario Negri Institute for Pharmacological Research
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2011-04
- **Primary completion:** 2014-10
- **Final completion:** 2014-10
- **Target enrollment:** 518 (ACTUAL)
- **Last updated:** 2015-12-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01809106

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01809106, "RCT Comparing the Analgesic Efficacy of 4 Therapeutic Strategies Based on 4 Different Major Opioids (Fentanyl, Oxycodone, Buprenorphine vs Morphine) in Cancer Patients With Moderate/Severe Pain, at the Moment of Starting 3rd Step of WHO Analgesic Ladder.". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01809106. Licensed CC0.

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