# A Prospective, Single-center, Open-label, Pilot Study to Compare the Effectiveness and Safety of Diuretics Add-On Strategy in Chronic Heart Failure Patients (DIOS 1)

> **NCT01817803** · NA · WITHDRAWN · sponsor: **Yonsei University**

## Conditions studied

- Congestive Heart Failure

## Interventions

- **DRUG:** furosemide/no spironolactone
- **DRUG:** metolazone/no spironolactone
- **DRUG:** furosemid/spironolactone
- **DRUG:** metolazone/spironolactone

## Key facts

- **NCT ID:** NCT01817803
- **Lead sponsor:** Yonsei University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2013-03
- **Primary completion:** 2015-06
- **Final completion:** 2015-12
- **Target enrollment:** 0 (ACTUAL)
- **Last updated:** 2014-02-19


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01817803

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01817803, "A Prospective, Single-center, Open-label, Pilot Study to Compare the Effectiveness and Safety of Diuretics Add-On Strategy in Chronic Heart Failure Patients (DIOS 1)". Retrieved via AI Analytics 2026-07-13 from https://api.ai-analytics.org/clinical/NCT01817803. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*