# Buspirone for the Treatment of Traumatic Brain Injury (TBI) Irritability and Aggression

> **NCT01821690** · PHASE4 · COMPLETED · sponsor: **Indiana University** · enrollment: 81 (actual)

## Conditions studied

- Traumatic Brain Injury

## Interventions

- **DRUG:** Buspirone
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01821690
- **Lead sponsor:** Indiana University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-05-15
- **Primary completion:** 2025-09-26
- **Final completion:** 2025-09-26
- **Target enrollment:** 81 (ACTUAL)
- **Last updated:** 2026-02-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01821690

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01821690, "Buspirone for the Treatment of Traumatic Brain Injury (TBI) Irritability and Aggression". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01821690. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*