Immune Disorder HSCT Protocol

Conditions

• Immune Deficiency Disorders
• Severe Combined Immunodeficiency
• Chronic Granulomatous Disease
• X-linked Agammaglobulinemia
• Wiskott-Aldrich Syndrome
• Hyper-IgM
• DiGeorge Syndrome
• Chediak-Higashi Syndrome
• Common Variable Immune Deficiency
• Immune Dysregulatory Disorders
• Hemophagocytic Lymphohistiocytosis
• IPEX
• Autoimmune Lymphoproliferative Syndrome
• X-linked Lymphoproliferative Syndrome

Interventions

• DRUG: Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan

Sponsor

Washington University School of Medicine