# The TRUST Study - Depression Substudy

> **NCT01853579** · PHASE4 · COMPLETED · sponsor: **Insel Gruppe AG, University Hospital Bern** · enrollment: 426 (actual)

## Conditions studied

- Subclinical Hypothyroidism
- Depression

## Interventions

- **DRUG:** Levothyroxine
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01853579
- **Lead sponsor:** Insel Gruppe AG, University Hospital Bern
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-03
- **Primary completion:** 2018-04-05
- **Final completion:** 2018-04-05
- **Target enrollment:** 426 (ACTUAL)
- **Last updated:** 2018-06-14

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01853579

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01853579, "The TRUST Study - Depression Substudy". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01853579. Licensed CC0.

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