# Therapy for Children With Advanced Stage Neuroblastoma

> **NCT01857934** · PHASE2 · COMPLETED · sponsor: **St. Jude Children's Research Hospital** · enrollment: 153 (actual)

## Conditions studied

- Neuroblastoma

## Interventions

- **DRUG:** cyclophosphamide
- **DRUG:** topotecan
- **BIOLOGICAL:** hu14.18K322A
- **PROCEDURE:** peripheral blood stem cell harvest
- **PROCEDURE:** surgical resection
- **DRUG:** cisplatin
- **DRUG:** etoposide
- **DRUG:** doxorubicin
- **DRUG:** vincristine
- **DRUG:** busulfan
- **DRUG:** melphalan
- **BIOLOGICAL:** peripheral blood stem cell transplantation
- **BIOLOGICAL:** natural killer cell infusion
- **RADIATION:** radiation therapy
- **BIOLOGICAL:** GM-CSF
- **BIOLOGICAL:** G-CSF
- **DRUG:** mesna
- **DRUG:** levetiracetam
- **BIOLOGICAL:** interleukin-2
- **DRUG:** Isotretinoin

## Key facts

- **NCT ID:** NCT01857934
- **Lead sponsor:** St. Jude Children's Research Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-07-05
- **Primary completion:** 2021-10-21
- **Final completion:** 2025-12-31
- **Target enrollment:** 153 (ACTUAL)
- **Last updated:** 2026-04-16

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01857934

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01857934, "Therapy for Children With Advanced Stage Neuroblastoma". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01857934. Licensed CC0.

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