# Effect of Curcumin on Dose Limiting Toxicity and Pharmacokinetics of Irinotecan in Patients With Solid Tumors

> **NCT01859858** · PHASE1 · COMPLETED · sponsor: **UNC Lineberger Comprehensive Cancer Center** · enrollment: 23 (actual)

## Conditions studied

- Advanced Colorectal Cancer

## Interventions

- **DIETARY_SUPPLEMENT:** curcumin
- **DRUG:** Irinotecan

## Key facts

- **NCT ID:** NCT01859858
- **Lead sponsor:** UNC Lineberger Comprehensive Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-06
- **Primary completion:** 2016-10-05
- **Final completion:** 2016-10-05
- **Target enrollment:** 23 (ACTUAL)
- **Last updated:** 2023-12-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01859858

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01859858, "Effect of Curcumin on Dose Limiting Toxicity and Pharmacokinetics of Irinotecan in Patients With Solid Tumors". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT01859858. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
