# ACE-Inhibitor Effects on Total Hip and Knee Arthroplasty Patients

> **NCT01867047** · NA · TERMINATED · sponsor: **Duke University** · enrollment: 59 (actual)

## Conditions studied

- Adverse Effects of Angiotensin-converting-enzyme Inhibitors
- Hypotension

## Interventions

- **DRUG:** ACE-I Cessation group
- **DRUG:** ACE-I Continuation group

## Key facts

- **NCT ID:** NCT01867047
- **Lead sponsor:** Duke University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2013-06
- **Primary completion:** 2016-06-24
- **Final completion:** 2016-06-24
- **Target enrollment:** 59 (ACTUAL)
- **Why stopped:** Following an interim analysis the study team felt that there was enough data that showed no significant difference.
- **Last updated:** 2017-09-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01867047

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01867047, "ACE-Inhibitor Effects on Total Hip and Knee Arthroplasty Patients". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01867047. Licensed CC0.

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