# Clinical Efficacy of Tranexamic Acid and ε-Aminocaproic Acid in Reducing Blood Loss Following Total Knee Replacement

> **NCT01873768** · PHASE4 · COMPLETED · sponsor: **Miller Orthopedic Specialists** · enrollment: 194 (actual)

## Conditions studied

- Osteoarthritis

## Interventions

- **DRUG:** Tranexamic Acid (TXA)
- **DRUG:** ε-Aminocaproic Acid (EACA)

## Key facts

- **NCT ID:** NCT01873768
- **Lead sponsor:** Miller Orthopedic Specialists
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-01
- **Primary completion:** 2015-12
- **Final completion:** 2015-12
- **Target enrollment:** 194 (ACTUAL)
- **Last updated:** 2016-03-21

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01873768

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01873768, "Clinical Efficacy of Tranexamic Acid and ε-Aminocaproic Acid in Reducing Blood Loss Following Total Knee Replacement". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT01873768. Licensed CC0.

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