# Intensity-Modulated Proton Beam Therapy or Intensity-Modulated Photon Therapy in Treating Patients With Stage III-IVB Oropharyngeal Cancer

> **NCT01893307** · PHASE3 · ACTIVE_NOT_RECRUITING · sponsor: **M.D. Anderson Cancer Center** · enrollment: 440 (actual)

## Conditions studied

- Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7
- Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7
- Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7

## Interventions

- **RADIATION:** Intensity-Modulated Radiation Therapy
- **RADIATION:** Intensity-Modulated Radiation Therapy
- **OTHER:** Laboratory Biomarker Analysis
- **RADIATION:** Photon Beam Radiation Therapy
- **RADIATION:** Proton Beam Radiation Therapy
- **OTHER:** Quality-of-Life Assessment

## Key facts

- **NCT ID:** NCT01893307
- **Lead sponsor:** M.D. Anderson Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2013-08-26
- **Primary completion:** 2031-12-31
- **Final completion:** 2031-12-31
- **Target enrollment:** 440 (ACTUAL)
- **Last updated:** 2026-02-24

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01893307

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01893307, "Intensity-Modulated Proton Beam Therapy or Intensity-Modulated Photon Therapy in Treating Patients With Stage III-IVB Oropharyngeal Cancer". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT01893307. Licensed CC0.

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