# Effect of the Combination of Methotrexate and Adalimumab on Reduction of Immunization in Ankylosing Spondylitis (COMARIS)

> **NCT01895764** · PHASE4 · COMPLETED · sponsor: **University Hospital, Tours** · enrollment: 110 (actual)

## Conditions studied

- Ankylosing Spondylitis

## Interventions

- **DRUG:** Adalimumab
- **DRUG:** Methotrexate

## Key facts

- **NCT ID:** NCT01895764
- **Lead sponsor:** University Hospital, Tours
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-03-20
- **Primary completion:** 2015-04-27
- **Final completion:** 2015-04-27
- **Target enrollment:** 110 (ACTUAL)
- **Last updated:** 2026-04-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01895764

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01895764, "Effect of the Combination of Methotrexate and Adalimumab on Reduction of Immunization in Ankylosing Spondylitis (COMARIS)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01895764. Licensed CC0.

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