# Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS

> **NCT01909141** · EARLY_PHASE1 · COMPLETED · sponsor: **Cairo University** · enrollment: 100 (actual)

## Conditions studied

- Polycystic Ovary Syndrome
- Infertility

## Interventions

- **DRUG:** induction of ovulation using letrozole-pioglitazone-metformin
- **DRUG:** induction of ovulation using clomiphene citrate-pioglitazone-metformin
- **RADIATION:** transvaginal ultrasound
- **OTHER:** body mass index (BMI) calculation
- **OTHER:** day 3: follicle stimulating hormone (FSH), luteinizing hormone (LH), thyroid stimulating hormone (TSH), total testosterone
- **OTHER:** pretreatment blood urea and serum creatinine
- **OTHER:** serum estradiol (E2) on day 12
- **OTHER:** serum progesterone on day 21
- **OTHER:** blood urea and serum creatinine every month

## Key facts

- **NCT ID:** NCT01909141
- **Lead sponsor:** Cairo University
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-08
- **Primary completion:** 2014-02
- **Final completion:** 2014-04
- **Target enrollment:** 100 (ACTUAL)
- **Last updated:** 2015-10-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01909141

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01909141, "Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT01909141. Licensed CC0.

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