# A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin in Participants With Osteoarthritis of the Knee

> **NCT01919164** · PHASE2 · COMPLETED · sponsor: **EMD Serono Research & Development Institute, Inc.** · enrollment: 549 (actual)

## Conditions studied

- Osteoarthritis, Knee

## Interventions

- **DRUG:** Sprifermin
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01919164
- **Lead sponsor:** EMD Serono Research & Development Institute, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-07-29
- **Primary completion:** 2016-05-05
- **Final completion:** 2019-05-07
- **Target enrollment:** 549 (ACTUAL)
- **Last updated:** 2020-07-13

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01919164

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01919164, "A Study to Investigate the Safety and Effectiveness of Different Doses of Sprifermin in Participants With Osteoarthritis of the Knee". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT01919164. Licensed CC0.

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