# Preventing TB-IRIS in High-risk Patients: a Randomized Placebo-controlled Trial of Prednisone

> **NCT01924286** · PHASE3 · COMPLETED · sponsor: **University of Cape Town** · enrollment: 240 (actual)

## Conditions studied

- Immune Reconstitution Inflammatory Syndrome
- HIV
- Tuberculosis

## Interventions

- **DRUG:** Prednisone
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01924286
- **Lead sponsor:** University of Cape Town
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-08-30
- **Primary completion:** 2016-04
- **Final completion:** 2017-04
- **Target enrollment:** 240 (ACTUAL)
- **Last updated:** 2018-01-19

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01924286

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01924286, "Preventing TB-IRIS in High-risk Patients: a Randomized Placebo-controlled Trial of Prednisone". Retrieved via AI Analytics 2026-06-13 from https://api.ai-analytics.org/clinical/NCT01924286. Licensed CC0.

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