# Randomized Controlled Trial of Tranexamic Acid in Total Knee Arthroplasty: Intravenous vs. Topical

> **NCT01940523** · PHASE4 · COMPLETED · sponsor: **Hospital for Special Surgery, New York** · enrollment: 640 (actual)

## Conditions studied

- Osteoarthritis

## Interventions

- **DRUG:** Topical Tranexamic Acid
- **DRUG:** Intravenous Tranexamic Acid

## Key facts

- **NCT ID:** NCT01940523
- **Lead sponsor:** Hospital for Special Surgery, New York
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-05
- **Primary completion:** 2015-12-28
- **Final completion:** 2017-05-16
- **Target enrollment:** 640 (ACTUAL)
- **Last updated:** 2019-11-27

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01940523

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01940523, "Randomized Controlled Trial of Tranexamic Acid in Total Knee Arthroplasty: Intravenous vs. Topical". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01940523. Licensed CC0.

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