# Acceleration of Insulin Action by Hyaluronidase During Closed-Loop Therapy

> **NCT01945099** · EARLY_PHASE1 · COMPLETED · sponsor: **Yale University** · enrollment: 13 (actual)

## Conditions studied

- Type 1 Diabetes

## Interventions

- **DEVICE:** ePID closed loop system
- **DRUG:** hyaluronidase
- **DRUG:** Lispro-PH20

## Key facts

- **NCT ID:** NCT01945099
- **Lead sponsor:** Yale University
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-09
- **Primary completion:** 2015-12
- **Final completion:** 2016-07
- **Target enrollment:** 13 (ACTUAL)
- **Last updated:** 2022-05-24


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01945099

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01945099, "Acceleration of Insulin Action by Hyaluronidase During Closed-Loop Therapy". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01945099. Licensed CC0.

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