# Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate

> **NCT01950520** · PHASE2 · COMPLETED · sponsor: **National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)** · enrollment: 47 (actual)

## Conditions studied

- Healthy Volunteers

## Interventions

- **DRUG:** Propranolol
- **DRUG:** Pindolol
- **DRUG:** Dantrolene
- **DRUG:** Magnesium Sulfate
- **DRUG:** Caffeine
- **DRUG:** Qsymia
- **DRUG:** Topiramate
- **BEHAVIORAL:** Phentermine
- **DRUG:** Naltrexone
- **DRUG:** Mirabegron 50mg
- **DRUG:** Mirabegron 200mg
- **DRUG:** Placebo Cohort 1
- **DRUG:** Placebo Cohort 2
- **DRUG:** Placebo for Mirabegron

## Key facts

- **NCT ID:** NCT01950520
- **Lead sponsor:** National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-02-07
- **Primary completion:** 2022-12-17
- **Final completion:** 2024-06-11
- **Target enrollment:** 47 (ACTUAL)
- **Last updated:** 2024-10-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01950520

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01950520, "Study of Human Non-Shivering Thermogenesis and Basal Metabolic Rate". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT01950520. Licensed CC0.

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