# Effects of Xenin-25 on Insulin Secretion and Gastric Emptying in Humans With and Without a Complete Truncal Vagotomy

> **NCT01951716** · PHASE1 · WITHDRAWN · sponsor: **Washington University School of Medicine**

## Conditions studied

- Does the Vagus Nerve Mediate the Effects of Xenin-25

## Interventions

- **DRUG:** Graded Glucose Infusion with Placebo
- **DRUG:** Graded Glucose Infusion with GIP Alone
- **DRUG:** Graded Glucose Infusion with xenin-25 alone
- **DRUG:** Graded Glucose Infusion with GIP plus xenin-25
- **DRUG:** Meal Tolerance Test with Placebo
- **DRUG:** Meal Tolerance Test with xenin-25

## Key facts

- **NCT ID:** NCT01951716
- **Lead sponsor:** Washington University School of Medicine
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2013-01
- **Primary completion:** 2018-07
- **Final completion:** 2018-07
- **Target enrollment:** 0 (ACTUAL)
- **Last updated:** 2018-04-26

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01951716

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01951716, "Effects of Xenin-25 on Insulin Secretion and Gastric Emptying in Humans With and Without a Complete Truncal Vagotomy". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT01951716. Licensed CC0.

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