# Long Term Safety of Naldemedine

> **NCT01965652** · PHASE3 · COMPLETED · sponsor: **Shionogi** · enrollment: 1246 (actual)

## Conditions studied

- Opioid-induced Constipation

## Interventions

- **DRUG:** Naldemedine
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01965652
- **Lead sponsor:** Shionogi
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-09-24
- **Primary completion:** 2016-01-12
- **Final completion:** 2016-01-12
- **Target enrollment:** 1246 (ACTUAL)
- **Last updated:** 2018-04-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01965652

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01965652, "Long Term Safety of Naldemedine". Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/clinical/NCT01965652. Licensed CC0.

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