# Effects of Nalmefene After Single Dose on the Blood Oxygen Level Dependent (BOLD) fMRI Signal in the Ventral Striatum to Reward Responding in the Monetary Incentive Delay Task (MIDT), in Non-treatment Seeking Subjects With Alcohol Dependence Following Alcohol Challenge

> **NCT01969617** · PHASE1 · COMPLETED · sponsor: **H. Lundbeck A/S** · enrollment: 22 (actual)

## Conditions studied

- Alcohol Dependence

## Interventions

- **DRUG:** Nalmefene 18 mg, then placebo
- **DRUG:** Placebo, then Nalmefene 18 mg

## Key facts

- **NCT ID:** NCT01969617
- **Lead sponsor:** H. Lundbeck A/S
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-11
- **Primary completion:** 2014-10
- **Final completion:** —
- **Target enrollment:** 22 (ACTUAL)
- **Last updated:** 2014-11-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01969617

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01969617, "Effects of Nalmefene After Single Dose on the Blood Oxygen Level Dependent (BOLD) fMRI Signal in the Ventral Striatum to Reward Responding in the Monetary Incentive Delay Task (MIDT), in Non-treatment Seeking Subjects With Alcohol Dependence Following Alcohol Challenge". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT01969617. Licensed CC0.

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