# Investigation of [6R] 5,10-methylenetetrahydrofolate (Arfolitixorin) as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX.

> **NCT01987102** · PHASE1,PHASE2 · COMPLETED · sponsor: **Isofol Medical AB** · enrollment: 18 (actual)

## Conditions studied

- Osteosarcoma

## Interventions

- **DRUG:** Calcium Folinate
- **DRUG:** [6R] 5,10-methylenetetrahydrofolate (arfolitixorin)

## Key facts

- **NCT ID:** NCT01987102
- **Lead sponsor:** Isofol Medical AB
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2013-12
- **Primary completion:** 2017-01-03
- **Final completion:** 2017-01-03
- **Target enrollment:** 18 (ACTUAL)
- **Last updated:** 2020-09-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01987102

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01987102, "Investigation of [6R] 5,10-methylenetetrahydrofolate (Arfolitixorin) as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX.". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT01987102. Licensed CC0.

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