# A Pharmacodynamic Study to Evaluate Neutrophil Distribution Kinetics and Function Following Single-Dose RoActemra/Actemra (Tocilizumab) in Healthy Volunteers

> **NCT01991990** · PHASE4 · COMPLETED · sponsor: **Hoffmann-La Roche** · enrollment: 18 (actual)

## Conditions studied

- Healthy Volunteer

## Interventions

- **DRUG:** placebo
- **DRUG:** tocilizumab [RoActemra/Actemra]

## Key facts

- **NCT ID:** NCT01991990
- **Lead sponsor:** Hoffmann-La Roche
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-05
- **Primary completion:** 2014-12
- **Final completion:** 2014-12
- **Target enrollment:** 18 (ACTUAL)
- **Last updated:** 2015-11-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01991990

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01991990, "A Pharmacodynamic Study to Evaluate Neutrophil Distribution Kinetics and Function Following Single-Dose RoActemra/Actemra (Tocilizumab) in Healthy Volunteers". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT01991990. Licensed CC0.

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