# Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair.

> **NCT01992146** · PHASE2 · COMPLETED · sponsor: **Rigshospitalet, Denmark** · enrollment: 9 (actual)

## Conditions studied

- Central Nervous System Sensitization
- Pain
- Hyperalgesia

## Interventions

- **DRUG:** Target-controlled naloxone-infusion
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT01992146
- **Lead sponsor:** Rigshospitalet, Denmark
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-11-11
- **Primary completion:** 2015-12-14
- **Final completion:** 2018-05-11
- **Target enrollment:** 9 (ACTUAL)
- **Last updated:** 2024-02-22

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT01992146

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT01992146, "Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair.". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT01992146. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
