# Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma

> **NCT02040376** · PHASE3 · COMPLETED · sponsor: **The Hospital for Sick Children** · enrollment: 24 (actual)

## Conditions studied

- Brain Tumor Treated With Cranial or Cranial-Spinal Radiation

## Interventions

- **DRUG:** Metformin
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02040376
- **Lead sponsor:** The Hospital for Sick Children
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-06-13
- **Primary completion:** 2017-12-15
- **Final completion:** 2017-12-15
- **Target enrollment:** 24 (ACTUAL)
- **Last updated:** 2025-07-16


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02040376

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02040376, "Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT02040376. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*