MEK Inhibitor MEK162 in Combination With Leucovorin Calcium, Fluorouracil, and Oxaliplatin in Treating Patients With Advanced Metastatic Colorectal Cancer
Conditions
- Recurrent Colon Cancer
- Recurrent Rectal Cancer
- Stage IVA Colon Cancer
- Stage IVA Rectal Cancer
- Stage IVB Colon Cancer
- Stage IVB Rectal Cancer
Interventions
- DRUG: MEK inhibitor MEK162
- DRUG: leucovorin calcium
- DRUG: fluorouracil
- DRUG: oxaliplatin
- OTHER: pharmacological study
- OTHER: Laboratory Biomarker Analysis
Sponsor
City of Hope Medical Center
Collaborators
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