# Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy

> **NCT02062632** · PHASE2 · TERMINATED · sponsor: **Mayo Clinic** · enrollment: 5 (actual)

## Conditions studied

- Esophageal Carcinoma
- Hypopharyngeal Carcinoma
- Laryngeal Carcinoma
- Lymphoma
- Mesothelioma
- Metastatic Malignant Neoplasm in the Lung
- Metastatic Malignant Neoplasm in the Pleura
- Metastatic Malignant Neoplasm in the Spinal Cord
- Non-Small Cell Lung Carcinoma
- Sarcoma
- Small Cell Lung Carcinoma
- Thymic Carcinoma
- Thymoma
- Thyroid Gland Carcinoma

## Interventions

- **DRUG:** Doxepin Hydrochloride
- **OTHER:** Placebo
- **OTHER:** Quality-of-Life Assessment
- **OTHER:** Questionnaire Administration

## Key facts

- **NCT ID:** NCT02062632
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2014-04-14
- **Primary completion:** 2015-05-29
- **Final completion:** 2017-11-06
- **Target enrollment:** 5 (ACTUAL)
- **Why stopped:** Poor accrual
- **Last updated:** 2019-10-01

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02062632

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02062632, "Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT02062632. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*