Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer

NCT02065687 · clinicaltrials.gov ↗

PHASE2,PHASE3

Phase

UNKNOWN

Status

469

Enrollment

NETWORK

Sponsor class

Conditions

Endometrial Adenocarcinoma
Endometrial Clear Cell Adenocarcinoma
Endometrial Serous Adenocarcinoma
Endometrial Undifferentiated Carcinoma
Recurrent Uterine Corpus Carcinoma
Stage III Uterine Corpus Cancer AJCC v7
Stage IIIA Uterine Corpus Cancer AJCC v7
Stage IIIB Uterine Corpus Cancer AJCC v7
Stage IIIC Uterine Corpus Cancer AJCC v7
Stage IV Uterine Corpus Cancer AJCC v7
Stage IVA Uterine Corpus Cancer AJCC v7
Stage IVB Uterine Corpus Cancer AJCC v7

Interventions

DRUG: Carboplatin
OTHER: Laboratory Biomarker Analysis
DRUG: Metformin Hydrochloride
DRUG: Paclitaxel
OTHER: Placebo Administration
OTHER: Quality-of-Life Assessment
OTHER: Questionnaire Administration

Sponsor

Gynecologic Oncology Group

Collaborators

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